Publications

Trond Aasen*, Edward Leithe, Sheila Graham, Petra Kameritsch, María D. Mayán, Marc Mesnil, and Kristin Pogoda and Arantxa Tabernero*. Connexins in Cancer: Bridging the Gap to the Clinic. Oncogene. Volume 38, 4429–4451 (2019). Abstract  Impact factor 6.933 (Q1)


Lourdes R Desviat, Cecilia Jiménez Mallebrera, Ainara Vallejo-Illarramendi, María D Mayán, Gisela Nogales-Gadea, Virginia Arechavala-Gomeza. EU-COST Actions: fostering international and national collaborative research for rare diseases. The Lancet Neurology. Correspondence. Vol 18, November 2019, 989-991. Fulltext. Impact factor 28.755 (D1).


Paula Carpintero-Fernandez, Marta Varela-Eirin, Alessandra Lacetera, Raquel Gago-Fuentes, Eduardo Fonseca, Sonsoles Martin-Santamaria*, and Maria D. Mayan*. New Therapeutic Strategies for Osteoarthritis by Targeting Sialic Acid Receptors. Biomolecules 2020, 10(4), 637; https://doi.org/10.3390/biom10040637. Fulltext. Impact factor 4.694 (Q1)


Adrián Varela-Vázquez, Amanda Guitián-Caamaño, Paula Carpintero-Fernandez, Eduardo Fonseca, Samar Sayedyahossein, Trond Aasen, Silvia Penuela and María D. Mayán*. Emerging functions and clinical prospects of connexins and pannexins in melanoma. BBA Reviews on Cancer. Available online 24 May 2020. Fulltext. Impact factor 6.887 (D1)


Marta Varela-Eirín, Adrián Varela-Vázquez, Carlos Luis Paíno, Antonio Casado-Díaz, Alfonso Calañas Continente, Virginia Mato, Eduardo Fonseca, Mustapha Kandouz, Alfonso Blanco, José Ramón Caeiro & María D. Mayán*. Senolytic activity of small molecular polyphenols from olive restores chondrocyte redifferentiation and promotes a pro-regenerative environment in osteoarthritis. Aging. Manuscript accepted 14 July 2020. Impact factor 5.515 (Q1)


Paula Carpintero-Fernandez, Raquel Gago-Fuentes, Hong Z. Wang, Eduardo Fonseca, Jose R. Caeiro, Virginijus Valiunas, Peter R. Brink and Maria D. Mayan*Intercellular communication via gap junction channels between chondrocytes and bone cells. Biochimica et Biophysica Acta (BBA) – Biomembranes. Volume 1860, Issue 12, December 2018, Pages 2499-2505. Abstract Impact factor 3.79 (Q1)


Marta Varela-Eirin, Jesus Loureiro, Eduardo Fonseca, Silvia Corrochano, Jose R. Caeiro, Manuel Collado and Maria D. Mayan*Cartilage regeneration and ageing: Targeting cellular plasticity in osteoarthritis. Ageing Research Reviews. 2018 Mar;42:56-71. doi: 10.1016/j.arr.2017.12.006. Epub 2017 Dec 16Abstract Impact factor 10.39 (D1)


Marta Varela-Eirín, Adrián Varela-Vázquez, Amanda Guitián-Caamaño, Carlos Luis Paíno, Virginia Mato, Raquel Largo, Trond Aasen, Arantxa Tabernero, Eduardo Fonseca, Mustapha Kandouz, José Ramón Caeiro, Alfonso Blanco and & María D. Mayán*Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis. Cell Death and Disease. 2018 Dec 5;9(12):1166. doi: 10.1038/s41419-018-1225-2. AbstractImpact factor 6.187 (Q1)


Marta Varela-Eirin; Adrian Varela-Vazquez; Marina Rodriguez-Candela Mateos; Anton Vila-Sanjurjo; Eduardo Fonseca; Jose Luis Mascareñas; Eugenio Vazquez; Maria D. Mayan*. Recruitment of RNA molecules by connexin RNA-binding motifs: implication in RNA and DNA transport through microvesicles and exosomes. BBA – Molecular Cell Research. Volume 1864, Issue 4, April 2017, Pages 728–736. Full Text. Impact factor 5.282 (Q1)


Angel Fernandez-Flores*, Adrian Varela, María D. Mayan, Eduardo Fonseca. Expression of connexin43 (Cx43) in the human hair follicle: emphasis on the Cx43 protein levels in the bulge and through the keratinisation process. Journal of Cutaneous Pathology. 2017 Sep 28. doi: 10.1111/cup.13050.  Impact factor 1.409 (Q3)


Raquel Gago-Fuentes; John Bechberger; Marta Varela-Eirin; Adrian Varela-Vazquez; Benigno Acea; Eduardo Fonseca; Christian Naus; María D. Mayán*. The C-terminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes. Oncotarget. Nov 8;7(45):73055-73067. doi: 10.18632/oncotarget. 12197. Full text Impact factor 6.359 (D1)


Adrian Varela-Vazquez; Paula Carpintero-Fernandez; Eduardo Fonseca*; María D. Mayán*. Connexins and pannexins as new therapeutic targets and diagnostic biomarkers for skin diseases. Piel. Elsevier 2016;31:254-62 – DOI: 10.1016/j.piel.2015.09.011

Gago-Fuentes R., Fernández-Puente P., Megias D., Carpintero-Fernández P., Mateos J., Blanco F.J.*  and  Mayan M.D.* Proteomic analysis of connexin 43 reveals novel interactors related to osteoarthritisMolecular & Cellular Proteomics. First Published on April 22, 2015, doi: 10.1074/mcp.M115.050211. [Full textImpact factor 6.564 (D1)


Mayan M.D.*, Gago-Fuentes R., Carpintero-Fernández P., Fernández-Puente P., Filgueira-Fernández P., Valiunas V., Brink P. Goldberg G. and Blanco F.J.* Articular chondrocyte network mediated by Gap Junctions: Role in metabolic cartilage homeostasis. Ann Rheum Dis. 2015 Jan;74(1):275-84. doi: 10.1136/annrheumdis-2013-204244. [ABSTRACT][CORRECTIONImpact factor 12.384 (D1)


Sunniyat Rahman, Zjwan Hussain, Aleksandra Dabrowska, María D. Mayán, Alan Boobis and Nabil Hajji * Global H3K9 Hypo-Acetylation and Promoter-Specific Hyper-Acetylation Facilitate E2F1-Mediated FOS Induction in Arsenic Trioxide Induced Cellular Transformation. Environmental Health Perspectives. 2015 May;123(5):484-92. doi: 10.1289/ehp.1408302. Epub 2015 Jan 9. Impact factor 7.977 (D1)


Gago-Fuentes R., Carpintero-Fernandez P., Goldring M.B., Brink P.R., Mayan M.D.* & Blanco F.J.* Biochemical evidence for gap junctions and Cx43 expression in immortalized human chondrocyte cell line: a potential model in the study of cell communication in human chondrocytes. Osteoarthritis and Cartilage. 2014 Feb 13. pii: S1063-4584(14)00041-7. doi: 10.1016/j.joca.2014.02.002. [ABSTRACT] Impact factor 4.165 (D1)

Mayan M.D.*, Carpintero-Fernandez P., Gago-Fuentes R., Martinez-de-Ilarduya O., Wang H.Z., Valiunas V., Brink P.R., Blanco F.J.* Human Articular Chondrocytes Express Multiple Gap Junction Proteins: Differential Expression of Connexins in Normal and Osteoarthritic Cartilage. Am J Pathol. 2013 Apr;182(4):1337-46.[ABSTRACT] Impact factor 4.591 (Q1)


Mayan M.D.*. RNAP-II Molecules Participate in the Anchoring of the ORC to rDNA Replication Origins. PLoS One. 2013;8(1):e53405. [ABSTRACT] [FULL TEXTImpact factor 3.234 (Q1)


Mayán M.D.*. RNAP-II transcribes two small RNAs at the promoter and terminator regions of the RNAP-I gene in Saccharomyces cerevisiae. Yeast. 2013 Jan;30(1):25-32. [ABSTRACTImpact factor 1.634 (Q2)


Freire-Picos M.A., Landeira-Ameijeiras V. and Mayan M.D.*. Stalled RNAP-II molecules bound to non-coding rDNA spacers are required for normal nucleolus architecture. Yeast. 2013 May 23. doi: 10.1002/yea.2961. [ABSTRACTImpact factor 1.634 (Q2)

Andres Clemente-Blanco, Nicholas Sen, Maria Mayan-Santos, Maria P. Sacristán, Bryony Graham, Adam Jarmuz, Adam Giess, Elizabeth Webb, Laurence Game, Dirk Eick, Avelino Bueno, Matthias Merkenschlager and Luis Aragón. Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription. Nature Cell Biology, 2011 13, 1450-1456. [ABSTRACTImpact factor 19.679 (D1)


Maria Mayan and Luis Aragon. Cis-interactions between non-coding ribosomal spacers dependent on RNAP-II separate RNAP-I and RNAP-III transcription domains. Cell Cycle 9:21, 4328-4337; November 1, 2010.[ABSTRACTImpact factor 4.565 (Q2)

Clemente-Blanco, A., Mayan-Santos, M., Schneider, D. A., Machin, F., Jarmuz, A., Tschochner, H. & Aragon, L. (2009). Cdc14 inhibits transcription by RNA polymerase I during anaphase. Nature, 2009 458, 219-222 (12 March 2009). [ABSTRACTImpact factor 41.456 (D1)


Mayan-Santos, M.D.; M.L. Martinez-Robles; P. Hernandez; J.B. Schvartzman and D.B. Krimer. A redundancy of processes that cause replication fork stalling enhances recombination at two distinct sites in yeast rDNAMolecular Microbiology, 2008. Jul; 69 (2): 361-75. [ABSTRACTImpact factor 4.419 (Q1)


Mayan-Santos, M.D.; M.L. Martinez-Robles; P. Hernandez; D.B. Krimer and J.B. Schvartzman. DNA is more negatively supercoiled in bacterial plasmids than in minichromosomes isolated from budding yeastElectrophoresis, 2007. Vol. 28, Issue 21, Pages 3845 – 3853. [ABSTRACTImpact factor 3.028 (Q1)


Rodriguez-Segade S, Rodriguez J, Mayan D, Camina F. Plasma albumin concentration is a predictor of HbA1c among type 2 diabetic patients, independently of fasting plasma glucose and fructosamine. Diabetes Care. 2005 Feb; 28(2):437-9. [ABSTRACTImpact factor 8.420 (D1)

Book Chapters

Mayan, M.* 2010. Drug-induced Permeabilization of S. cerevisiae. Curr. Protoc. Mol. Biol. 92:13.2B.1-13.2B4.  Invited article by the editorial of Curr. Protoc. Mol. Biol. (Serial Major reference work).[ABSTRACT]


Maria D. Mayan*, Alexandra McAleenan and Priscilla Braglia. Drug-Induced Permeabilization in fungi. Laboratory Protocols in Fungal Biology: Current Methods in Fungal Biology. 2013, pp 519-522. © Springer Science+Business Media, LLC 2013. [ABSTRACT]


Maria D. Mayan* and Luis Aragon. Chromosome Conformation Capture (3C) of Tandem Arrays in Yeast. Yeast Genetics: Methods and Protocols, Methods in Molecular Biology, vol 1205, 2014, pp 219-229. © Springer Science+Business Media New York 2014. [ABSTRACT]

Patents

MARIA D. MAYAN; FRANCISCO J. BLANCO; PAULA CARPINTERO; GARY S. GOLBERG. COMPOSITIONS AND METHODS TO TREAT INFLAMMATORY JOINT DISEASE. PCT/US2014/045229. International Filing Data: 02.07.2014. [PATENTSCOPE]


MARIA D. MAYAN; BENIGNO ACEA NEBRIL; MARTA VARELA; MARINA RODRIGUEZ-CANDELA; CARLOTA CZESTOKOWA DIAZ; EDUARDO FONSECA; LUIS BARRIO; ADELA ESCUDERO. COMPOSITION FOR THE TREATMENT OF NEGATIVE SIDE EFFECTS OF CHEMOTHERAPY AN/OR RADIOTHERAPY. PCT/ES2020/070269 April 27, 2020.


MARIA D. MAYAN; MARTA VARELA EIRIN; ALEJANDRO CASTRO IGLESIAS; EUGENIO VÁZQUEZ SENTÍS; JOSÉ LUIS MASCAREÑAS CID; SORAYA LEARTE AYMAMÍ; JOSÉ RAMÓN CAEIRO REY. PEPTIDES FOR USE AS SENOTHERAPEUTIC AGENTS. PCT/EP2020/071242.


CAMIÑA DARRIBA, MANUEL FÉLIX; MAYÁN SANTOS, MARÍA DOLORES; RODRÍGUEZ-SEGADE VILLAMARÍN, SANTIAGO. METHOD FOR IDENTIFICATION OF THE ALLELOS M S AND Z OF ALPHA-1-ANTITRYPSIN USING RESTRICTION ENZYMES. (MÉTODO PARA IDENTIFICACIÓN DE LOS ALELOS M, S Y Z DE  ALPHA-1-ANTITRIPSINA CON ENZIMAS DE RESTRICCIÓN). SPANISH PATENT AND TRADE MARK OFFICE. PUBLICATION NUMBER: 2 228 217. SANTIAGO DE COMPOSTELA UNIVERSITY (USC). DATE; 04/ 01/ 2005.